CRUK RadNet City of London Seminar Series #20

‘Current and future concepts in the management of rectal cancer’

Friday, 31st March 2023 at 3:00 – 4:00pm GMT



Join the Zoom Seminar:

Meeting ID: 961 5901 1871
Passcode: 045331

Hosted by Dr Anthony Kong, Reader and Honorary Consultant Clinical Oncologist at Kings College London, we warmly welcome Professor Dr Emmanouil Fokas  to join us and deliver a seminar talk on ‘‘Current and future concepts in the management of rectal cancer’


Preoperative chemoradiotherapy and short course radiotherapy to patients with clinically staged TNM stage II/III rectal cancer has resulted in excellent local control. However, as the management of rectal cancer is shifting to organ preservation, various strategies have been explored to enhance clinical complete response. Here, the evidence on radiosensitizing options and intensified concomitant chemotherapy to achieve complete response and improve clinical outcome will be summarized. Studies using novel therapeutic agents will be discussed as well.

About our speaker:

Emmanouil Fokas is full Professor of Clinical Radiation Oncology at the Goethe University Frankfurt and Deputy Clinical Chair at the Department of Radiotherapy and Oncology, University Hospital Frankfurt in Germany. He holds an MD from the Philipps University Marburg, Germany and a PhD (DPhil) in Clinical Oncology and Radiobiology from the University of Oxford, UK. He is a full-time clinician, also heavily involved in translational research. His scientific interests are gastrointestinal and translational radiation oncology with focus on the tumor microenvitonment, and is the PI and co-PI of several Phase I-III trials in rectal and anal cancer. Dr. Fokas has obtained several third-party funding grants in excess of 7M Euro. Dr Fokas is co-founding member of the Frankfurt Cancer Institute (FCI; 115M Euro) established in 2019 after a highly competitive process. Dr Fokas serves on the scientific board of several national and international societies and specialist groups. He has given over 120 invited seminars and lectures throughout the world and is a regular contributor to international medical publications and meetings. He has (co)authored over 150 peer-reviewed manuscripts, including first and last authorships in Lancet Oncology, Journal of Clinical Oncology, Nature Review Clinical Oncology, and JAMA Oncology.